摘要
大戟属植物在全世界分布有2000多种,对于本属植物二萜类成分及生物活性的综述报道较多,但是还未见关于三萜类化学成分及生物活性的综述报道。本文综述了该属植物各种类型三萜化合物(羊毛脂烷型、环阿尔廷烷型、大戟烷型、甘遂烷型、齐敦果烷型、乌苏烷型及羽扇豆烷型等)的化学性能以及抗肿瘤、抗炎抗菌、抗病毒等主要生物活性的研究。
More than two thousand Euphorbia species are distributed in the world, which are used in folk medicine to cure skin diseases, edema, tuberculosis, and as a purgative and diuretic medicine in our country. Many reviews are about investigations of chemicals and pharmacologic actions of deterpenoids, however, the review on chemicals and bioactivities of triterpenoids in Euphorbia has not been reported before. The paper summarizes studies of the chemical structures of triterpenoids ( lanostane-type, cycloartane-type, euphane-type, tirueallane-type, oleanane-type,ursane-type and lupine-type) and their major bioactivities including anti-tumor, anti-inflammatory, anti-bacterial and anti-virus. The chemistry and bioactivities of Euphorbia triterpenoids still have great space to study.
出处
《化学进展》
SCIE
CAS
CSCD
北大核心
2010年第5期877-887,共11页
Progress in Chemistry
基金
植物化学与西部植物资源持续利用国家重点实验室开放课题(No.P2008-KF05)
西部博士资助项目
中科院知识创新工程领域前沿项目资助