血清半胱氨酸蛋白酶抑制剂C、尿微量白蛋白在诊断肝源性糖尿病患者早期肾损伤中的临床意义

The Clinical Significance of CysC and U-MAlb in Diagnosis of Early Diabetes Nephro Pathy in Patients with Hepatitis

目的:探讨肝源性糖尿病患者血清半胱氨酸蛋白酶抑制剂C(CysC)、尿微量白蛋白(U-MAlb)浓度改变与肾脏损害之间的关系。方法:分别检测97例慢性肝炎患者(慢性肝炎组)、155例肝源性糖尿病患者(肝源性糖尿病组)和20例正常对照组血清Cysc(透射比浊法)、U-MAlb(散射比浊法)、糖化血红蛋白(高效液相色谱法)的浓度。结果:肝源性糖尿病组外周血CysC、U-MAlb水平显著高于慢性肝炎组和对照组。结论:肝源性糖尿病患者血清CysC、U-MAlb水平升高提示患者存在不同程度的肾脏损害。

Objective:To study the clinical significance of serum CysC and uria-micro-Albmin(U-MAlb)in diagnosis diabetes in patients with hepatitis.Method:Detected the value of CysC and Uria-Micro-Albmin(U-MAlb)with scattering nephelometry.Results:The level of CysC(1.78±0.48mg/L)and U-MAlb(10.46±5.31mg/L)of diabetes in patients with hepatitis were significantly higher(P<0.01)than group with hepatitis(1.01±0.35 mg/L,4.59±3.22 mg/L)and normal(0.70±0.29 mg/L,4.39±2.98 mg/L).Conclusion:The CysC and uriamicro-Albmin were veryi mportant of diabetesin patients with hepatitis.