摘要
在体内，正常红细胞具有很强的变形能力，能够挤过直径比它小得多的毛细血管。红细胞变形能力的好坏直接影响血液循环的外周阻力。对在体红细胞运动变形的研究是病理生理学研究和临床应用的需要。本文应用图像序列分析技术，提出了一整套基于轮廓的“显微图像中可变形物体动态跟踪的方法”，并将这一方法应用于红细胞进入毛细血管运动全过程的轮廓跟踪。
Normal red blood cells are highly deformable in vivo. They can pass smoothly through the capillaries whose diameters are less than theirs. Whether their deformability is good or bad affects the peripheral resistance of blood circulation directly. It is the demand of pathology, physiology and clinic medicine to study the movement and deformability of red blood cells in vivo. With the aid of the technique of image sequence processing, based on the contours, we first presented a new method of movement and deformation tracking for deformable objects in microscopic images. We also applied this method to the contour tracking of red blood cells, when they were entering the capillaries.
出处
《中国生物医学工程学报》
CAS
CSCD
北大核心
1998年第2期167-172,共6页
Chinese Journal of Biomedical Engineering
关键词
微循环
红细胞变形
局部能量法
蛇行模型
Microcirculation
Deformation of red blood cells
Local energy method
Snake model
Contour
