代谢综合征及相关因子与急性脑血管病研究

Correlation between metabolic syndrome and acute cerebrovascular disease

目的探讨代谢综合征及相关因子在急性脑血管病人中的发生情况。方法收集急性住院脑梗塞、脑出血患者各200例及健康体检者80例并采集腰围、血压、血糖、血脂等资料。结果脑梗塞组分别和脑出血组、对照组比较代谢综合征发生率均有显著性差异(P<0.05);而脑出血和对照组比较无统计学意义(P>0.05)。脑梗塞相关的独立危险因素依次为:代谢综合征、高血压病、高血糖、甘油三酯增高、高密度脂蛋白降低;而脑出血仅为高血压病。结论代谢综合征是脑梗塞的独立危险因素,代谢紊乱程度越重,患脑梗塞的风险越大。代谢综合征与脑出血无明显相关。

Objective To investigate the relationship between metabolic syndrome and acute cerebrovascular disease.Methods 200 patients with cerebral infarction（CI）and 200 patients with intracerebra] hemorrhage（ICH）were selected as study objects,80 age and gender-matched healthy subjects were used as control group at the same period.The levels of blood pressure,blood glucose.Waistline and blood lipids were measured in all the patients.Results There were significant difference in the rate of the metabolic syndrome between CI and control groups, and also CI and ICH groups （/}〈0.05） except that there were no statistical significance between ICH and control groups （P〉0.05）.The independent risk factors of CI as follows： hypertension,metabolic syndrome, high blood glucose, ele- vated triglyceride,lower high-density lipoprotein; The independent risk factor of ICH was hypertension only.Conclusion Metabolic syndrome is an independent risk factor for cerebral infarction.Metabolic syndrome has nothing to do with intracerebral hemorrhage. More severe degree of metabolic disorder, the greater risk of suffering from cerebral infarction.