鼻内镜下鼻窦开放术后恶心呕吐的原因分析及预防

Causes and Prevention of Postoperative Nausea and Vomiting in Patients Underwent Opening Sinus Surgery

目的:探讨鼻内镜下鼻窦开放术后恶心呕吐的原因及各种止吐药的预防效果。方法:选择120例在气管内全麻下进行鼻内镜下鼻窦开放术的患者,随机分成3组,每组40例。Ⅰ组为静注托烷司琼5mg,Ⅱ组静注甲氧氯普胺10mg,Ⅲ组静注生理盐水5mL。结果:Ⅰ组病人术后24h恶心呕吐的发生率明显少于其他两组。结论:托烷司琼能有效预防各种原因引起的鼻内镜下鼻窦开放术后恶心呕吐。

Objective：To study the causes of postoperative nausea and vomiting（PONV）in patients underwent opening sinus surgery,and evaluate the preventive effect of two antiquing drugs.Method：120 patients underwent opening sinus surgery by general anesthesia were investigated.The patients were divided into three groups.Each group with 40 cases.Patients in group I were treated with intravenous tropisetron 5mg,those in group Ⅱwere treated with intravenous metoclopramide 10mg,and those in groupⅢ were treated with intravenous normal saline 5mL.PONV was observed and recorded within 24 hours postoperatively.Result：The incidence of group I was significantly lower than that in group Ⅱ or Ⅲ（P〈0.01）.Conclusion：Tropisetron can effectively prevent PONV in opening sinus surgery.