两种不同方法治疗不稳定型心绞痛的疗效观察

Observing the Effect of Two Ways in Treating Patients with Unstable Angina Pectoris

目的:探讨两种不同的方法治疗不稳定型心绞痛(UAP)的临床效果。方法:将2008年1月至2010年1月间在我院住院治疗的不稳定型心绞痛患者68例随机分为观察组和对照组,对照组给予低分子肝素钙注射液及辛伐他汀治疗,观察组给予氯吡格雷片及瑞舒伐他汀治疗。结果:治疗后观察组患者在TC、LDL-C及HDL-C改善方面明显优于对照组,两组比较差异具有统计学意义(P>0.05)。观察组总有效率为97.06%,对照组为82.35%,两组比较差异具有统计学意义(P>0.05);观察组心血管事件发生率为2.94%,对照组为17.65%,两组比较差异具有统计学意义(P>0.05);两组患者均未见明显的药物不良反应。结论:氯吡格雷片及瑞舒伐他汀治疗不稳定型心绞痛的临床效果更好,值得应用。

Objective：To investigate the effect of two ways in treating cases with unstable angina pectoris.Method：The 68 cases with unstable angina pectoris in our hospital from January in 2008 to January in 2010 were divided into the observing group and the control group,the observing group received the treatment of nadroparin calcium injection combined with simvastatin and the control group received the treatment of clopidogrel combined with rosuvastatin.Result：The TC,LDL-C and HDL-CFEV1 in the observing group was superior to that in control group,and there was significant difference in them respectively（P〈0.05）.The total effective rate was 97.06% in observing group and 82.35% in control group,and there was significant difference in them（P〈0.05）.The cadiovascular incident rate was 2.94% in observing group and 17.65% in control group,and there was significant difference in them（P〈0.05）.Conclusion：The effect of nadroparin calcium injection combined with simvastatin in treating patients with unstable angina pectoris is superior to that of clopidogrel combined with rosuvastatin,so they are worth being used widly.