手术切除与经皮射频消融在小肝癌治疗中的价值探讨

Discussion on the Value of Surgical Resection and Percutaneous Radiofrequency Ablation in the Treatment of Small Hepatocellular Carcinoma

目的评价手术切除与经皮射频消融(PRFA)在小肝癌治疗中的价值。方法我院小肝癌患者99例分为两组,分别给于手术切除和PRFA,对两组术后不良反应、术后1年复发率进行比较。结果两组患者术后不良反应,包括术后体温恢复时间,ALT升高例数,胆红素升高例数,经比较无差异;对于直径≤3cm的肿瘤,手术治疗与PRFA治疗组患者术后1年的肿瘤复发率差异没有显著性;但是直径3～5cm的肿瘤,手术治疗组在术后1年的肿瘤复发率明显低于PRFA治疗组。结论手术治疗与PRFA均是一种创伤小、恢复快、安全性高的治疗方法 ,对于肿瘤直径≤3cm的,两者疗效等同;对于肿瘤直径3～5cm的,以手术治疗为宜。

Objective To evaluate the value of surgical resection and percutaneous radiofrequency ablation （PRFA） in the treatment of small hepatocellular carcinoma.Methods 99 cases with small hepatocellular carcinoma were divided into 2 groups and surgical resection and percutaneous radiofrequency ablation were performed on the patients in the 2 groups respectively;the post-operation side-effect and the reoccurrence 1 year after operation were compared between the 2 groups.Results There existed no difference between the 2 groups in post-operation side-effect,including the time of restoring normal body temperature,the case number of ALT increase and bilirubin;for those cases with the tumor diameter ≤3cm,the reoccurrence 1 year after operation had no significant difference;but for those with the tumor diameter over 3cm to 5cm,the reoccurrence 1 year after surgical resection was obviously lower than that 1 year after percutaneous radiofrequency ablation.Conclusions Both surgical resection and percutaneous radiofrequency ablation are safe treatment for small hepatocellular carcinoma with injury and quick recovery and the 2 have the same effect on tumor with the diameter ≤3cm and surgical resection is of better effect on the tumor with the tumor diameter about 3cm to 5cm.