中医辨证配合西药治疗早期糖尿病肾病临床观察

TCM with Western Medicine Treatment of Early Diabetic Nephropathy

目的:观察补肾益元汤配合西药治疗早期糖尿病肾病的临床疗效。方法:将60例随机分为两组,在常规控制饮食、血糖、血压的基础上,对照组给予福欣普利口服治疗,治疗组在对照组的基础上给予补肾益元汤,观察3个月。结果:对照组总有效率56.67%,治疗组总有效率83.33%,两组比较差异显著(P<0.05)。福欣普利与补肾益元汤合用有明显升高糖尿病肾病患者血浆白蛋白和降低尿蛋白的作用,补肾益元汤还有降低血胆固醇和甘油三酯等作用,福欣普利则无此作用,二者合用对糖尿病肾病患者的血肌酐还有降低作用。结论:补肾益元汤通过升高糖尿病肾病患者血浆白蛋白和降低尿蛋白的作用以及降低血脂、血肌酐减轻肾小球的损害,延缓肾功能的减退,提高了糖尿病肾病患者的临床有效率。

Objective：To observe the Bushen Yuan Tang in Treating the clinical efficacy of early diabetic nephropathy.Methods：60 cases were randomly divided into two groups,in the conventional control diet,blood sugar,blood pressure,based on the control group was given Fuxinpuli oral treatment,the treatment group in the control group on the basis of granting Bushen Yuan Tang,observation 3 months.Results：In control group,the total efficiency of 56.67%,treatment group,the total efficiency of 83.33%,a significant difference between the two groups （P〈0.05）.Fuxinpuli combination with Bushen Motoyu significantly elevated in patients with diabetic nephropathy reduces urinary protein,plasma albumin and the role of Bushen Yuan Tang also lower blood cholesterol and triglycerides such as the role of Fuxinpuli then there is no such effect,the two combined in patients with diabetic nephropathy have reduced the role of serum creatinine.Conclusion：Bushen Motoyu by raising plasma albumin in patients with diabetic nephropathy and reduce the role of urine protein and lower blood lipids,serum creatinine reduce glomerular damage,delay decreased renal function improved in patients with diabetic nephropathy and efficient clinical.