健康成人左右心室整体心功能的64排螺旋CT研究

Assessment of Global Left and Right Ventricular Function with 64 Multi-detector Row Computed Tomography in Healthy Adults

探讨健康国人左右心室整体心功能,建立功能参数的CT参考值。对58例成人健康(男女各28例)心脏行64层螺旋CT检查,重建心动周期十个时相心脏短轴位,用心功能软件勾画左右室心内外膜边界,计算左右心室整体功能指标。左右心室舒张末期容积、收缩末期容积、每搏量及心肌质量男性均大于女性,有显著性差异(P<0.05);但心输出量、射血分数男女无显著性差异。在同一性别组中,左室的心肌质量大于右室(P<0.01)。左右心室收缩末期容积与体重指数呈负相关,相关系数为-0.54和-0.53;左右心室每搏量、射血分数与体重指数呈正相关,相关系数分别为0.87/0.97和0.69/0.62。正常左右心室整体收缩功能与性别、个体大小有关。

To evaluate the global left and right ventricular function and establish the CT reference data of global ventricular function parameters in normal people,56 normal subjects（male,28 cases;female,28 case） were scanned with retrospective ECG gated 64-detector row CT.Ten time-phases in the cardiac cycle were reconstructed and short-axis images were acquired.On the cardiac analysis software,endo-cardium and epi-cardium of left and right ventricle were delineated and global function parameters were calculated.Left and right ventricular end-diastolic volume（LV/RVEDV）,end-systolic volume（LV/RVESV）,stroke volume（LV/RVSV）,and wall mass（LV/RVWM） were significantly greater（P0.05） in men than in women,but cardiac output（LV/RVCO） and ejection fraction（LV/RVEF） exhibited no difference in women and men.In man group and woman group,LVWM was greater than RVWM（P0.01）.LVESV,RVESV and body mass Index（BMI） were shown to have significant negative-correlation;the correlation coefficient=-0.54 and r=-0.53.LV/RVSV,LV/RVEF and BMI were noted to have significant positive-correlation;the correlation coefficients were 0.87/0.97 and 0.69/0.62,respectively.The normal global left and right ventricular functions differ significantly according to gender and body size.