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苦碟子联合奥扎格雷钠治疗2型糖尿病下肢血管病变疗效观察 被引量:2

Effects of sowthistle-leaf ixeris seedling in combination with sodium ozagrel on type 2 diabetes patients with crura vascular diseases
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摘要 目的:研究苦碟子联合奥扎格雷钠在治疗2型糖尿病下肢血管病变的临床疗效和对患者血液流变学的影响。方法:将110例2型糖尿病下肢血管病变患者随机分为两组,治疗组(n=55)予以常规措施并加苦碟子注射液联合奥扎格雷钠注射液治疗,对照组(n=55)以常规措施并加复方丹参注射液治疗。观察治疗前后临床表现、踝臂指数(ABI)和血液流变学的变化。结果:两组治疗后临床表现较治疗前有改善,但治疗组疗效较对照组更显著(P<0.05);两组治疗后ABI和血液流变学指标均有改善,与治疗前比较具有显著性,但治疗组的改善差异更具有显著性(P<0.05)。结论:苦碟子联合奥扎格雷钠可显著改善下肢血液循环的高凝、高黏状态,是治疗糖尿病下肢血管病变的有效途径。 Objective: To observe the effects of sowthistle-leaf ixeris seedling in combination with sodium ozagrel on type 2 diabetes patients with crura vascular diseases.Methods:110 cases of type 2 diabetes patients with cruravascular diseases were randomly divided into treatment group (n=55) who were given normal measures and sowthistle-leaf ixeris seedling in com bination with sodium ozagre,and control group(n=55) who were given common measures and compound danshen injection. Investigated the change of clinical manifestation,ABI and hemorheology before and after treatment. Results:Both groups were improved on ABI and hemorheology compared with before treatment (P〈0.05), the treatment group were signfiantly better than those in the control group (P〈0.05).Conclusion:Sowthistle-leaf ixeris seedling in combination with sodium ozagrel has better action on improving hemorheology. It is an effective method for treating diabetes patients with crura vascular diseases.
出处 《中国当代医药》 2010年第14期69-71,共3页 China Modern Medicine
关键词 苦碟子 奥扎格雷钠 糖尿病下肢血管病变 Sowthistle-leaf ixeris seedling Sodium ozagrel Diabetes patients with crura vascular diseases
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