心肌酶谱和肌钙蛋白I联合检测对诊断急性心肌梗死的临床应用价值

Diagnostic value of cardiac enzymes and troponin I combination detection in acute myocardial infarction

目的:探讨心肌酶谱和肌钙蛋白I联合检测在急性心肌梗死早期诊断的临床应用价值。方法:对2009年1月～2010年1月本院就诊的205例就诊的急性胸痛患者同时联合检测心肌酶谱(AST、LDH、CK、CK-MB、HBDH、Mg2+)和肌钙蛋白I(cTnI),比较其检测结果对于诊断急性心肌梗死的特异性和灵敏性。结果:205例就诊的急性胸痛患者中经确诊120例为急性心肌梗死,其中103例心肌酶谱升高,敏感性为85.8%,112例肌钙蛋白I阳性,敏感性为93.3%。120例阴性对照中,10例心肌酶谱升高,特异性为91.7%,5例肌钙蛋白I阳性,特异性为95.8%。结论:心肌钙蛋白I与心肌酶谱的联合应用提高了临床对AMI诊断的及时性和准确性。

Objective： To explore the clinical value of cardiac enzymes and troponin I combination detection in the diagnosis of acute myocardial infarction （AMI）. Methods： Gather 205 cases of acute chest pain patients from January 2009 to January 2010, at while take its blood into be measured the cardiac enzymes （AST, LDH, CK, CK-MB, HBDH, Mg^2＋） and troponin I （cTnI） levels, compared their specificity and sensitivity for the diagnosis of acute myocardial infarction. Results： In 205 acute chest pain patients, 120 patients confirmed to acute myocardial infarction, 103 patients of cardiac enzymes rise, the sensitivity was 85.8% , Troponin I was positive in 112 patients, the sensitivity was 93.3%. Among 120 cases negative control, 10 cases of cardiac enzymes rised, the specificity was 91.7% , 5 cases of troponin I was positive, the specificity was 95.8%. Conclusion： Troponin and cardiac enzymes combination detection improved the accuracy of clinical diagnosis of AMI.