硝酸甘油微量注射器持续泵注治疗重症充血性心力衰竭临床观察

Observation of Nitroglycerin micro-syringe infusion in the treatment of severe congestive heart failure

目的:观察治疗重症充血性心力衰竭(CHF)的疗效方法。方法:选择50例充血性心力衰竭心功能Ⅲ～Ⅳ级住院患者,均进行病因和对症治疗并按CHF常规处理,包括低盐饮食,在应用洋地黄、利尿剂和血管紧张素转换酶抑制剂(ACEI)的基础上,应用硝酸甘油微量注射器以2～7mg/h持续泵注,连续7d。动态观察血压、临床症状、体征。结果:治疗1周后,总有效率为94%。结论:硝酸甘油注射液可有效治疗重症CHF,能明显改善患者心脏功能,短期应用副作用少、安全性好。

Objective： To observe the efficacy of methods in the treatment of severe congestive heart failure （CHF）. Methods： 50 cases of cardiac function in congestive heart failure class Ⅲ～Ⅳ inpatients,were carried out according to CHF etiology and symptomatic treatment of conventional treatment,including low-salt diet, on the bases of the application of digi- talis, diuretics and angiotension comverting enzyme inhibitors （ACEI）, used nitroglycerin micro-syringe with 2-7 mg/h continuous infusion,continuous 7 days. Dynamic observation of blood pressure,clinical symptoms and signs. Results： After one week,with a total effective rate of 94%. Conclusion： Nitroglycerin injection is effective for the treatment of severe CHF patients,it can significantly improve cardiac function in patients, short-term application of less side effects and safe.