低热量营养支持用于高龄老年患者的可行性

Feasibility of hypocaloric nutrition support in elderly patients

目的 探讨对大于85岁高龄老年患者进行低热量营养支持的可行性。方法对16例85岁以上高龄老年患者进行低热量营养支持4周。总热量75～96kJ·kg^-1·d^-1，其中葡萄糖占44％～59％（137—207g·d^-1），脂肪占26％～42％（40～67g·d^-1），蛋白质占14％～16％（0．7～0．9g·kg^-1·d^-1），非蛋白热量：氮量为131：1～150：1。比较低热量营养支持前后患者血常规、血生化、凝血功能的变化。结果低热量营养支持能较好地维持高龄老年患者血浆蛋白、血脂、淋巴细胞水平，对肝肾功能、凝血功能无明显影响。结论4周低热量营养支持对85岁以上高龄老年患者安全有效。

Objective To investigate the feasibility of hypocaloric nutrition support in elderly patients. Methods Sixteen elderly patients （ 〉 85 years） were treated with hypoealorie nutrition for 4 weeks. The calorie intake was 75-96 kJ ·kg^-1· d ^-1, including 44% -59% of carbohydrates （ 137-207 g·d^-1） , 26% -42% of lipids （40-67 g ·d^-1） , and 14% -16% of proteins （0.7-0. 9 g· kg^-1· d ^-1 ）. Nonprotein calorie-to-nitrogen ratio was 131：1-150：1. After 4 weeks of treatment, changes in blood routine test, biochemistry, and clotting function were compared with those before hypocaloric nutrition support. Results After hypocaloric nutrition support, the plasma proteins, blood fats, and lymphocytes in these 16 elderly patients were well maintained, and no obvious adverse effect on clotting function or liver/kidney functions was observed. Conclusion Hypocaloric nutrition support is safe and effective for elderly patients who are older than 85 years.