复方甘草酸联合苦参素治疗慢性乙型肝炎52例疗效观察

Clinical observation of Compound Glycyrrhizin and Oxymatrine in the treatment of 52 cases with chronic hepatitis B

目的:探讨复方甘草酸苷联合苦参素治疗慢性乙型肝炎的疗效。方法:将104例慢性乙型肝炎患者随机均分为治疗组与对照组。对照组给予复方甘草酸苷注射液治疗,治疗组在对照组基础上加用苦参素治疗,两组疗程均为3个月。结果:治疗组在改善临床症状、肝功能指标变化情况方面均优于对照组(P<0.05),苦参素联合复方甘草酸苷治疗慢性乙型肝炎有良好的疗效,且两组患者均无明显的不良反应。结论:复方甘草酸苷联合苦参素治疗慢性乙型肝炎能够明显改善肝功能、抑制肝细胞纤维化、防止肝硬化发生,值得临床推广应用。

Objective：To explore the effect of Compound Glycyrrhizin and Oxymatrine in the treatment of chronic hepati-tis B.Methods：104 cases of chronic hepatitis B patients were randomly divided into treatment group and control group.The control group was given Compound Glycyrrhizin injection therapy,the treatment group used Oxymatrine on the basis of therapy in the control group,the two groups were treated for 3 months.Results：The treatment group in improving the clin-ical symptoms,liver function and normalization rate after treatment were statistically superior to the control group（P〈0.05）,Compound Glycyrrhizin and Oxymatrine in the treatment of chronic hepatitis B had a good effect,and there were no signif-icant adverse reactions in the patients of two groups.Conclusion：Compound Glycyrrhizin and Oxymatrine in the treatment of chronic hepatitis B can improve liver function,inhibit liver fibrosis,prevention of cirrhosis,it is worthy of applying for clinical.