ART后自然减胎的相关因素及妊娠结局分析

Correlation factors and consequences of the spontaneous pregnancy reduction in assisted reproductive technology

目的探讨辅助生殖技术(ART)助孕妊娠后发生自然减胎(SPR)发生的相关因素和对妊娠结局的影响。方法回顾性分析2003年1月-2008年12月我院ART术后妊娠的3506例患者,分析与SPR有关的因素和妊娠结局。结果 ART后SPR的发生与移植的胚胎质量有关;发生SPR后出生低体重儿和早产的可能性增大;SPR发生越晚,其产科异常结局风险越大。结论选择优质胚胎的单胚胎移植(SET),可能是有效避免多胎妊娠,减少SPR发生的根本之举。此外,在对多胎妊娠实行选择性减胎时应充分考虑SPR的发生时间及发生率。

Objective： To investigate the risk factors and consequences of spontaneous pregnancy reduction in assisted reproductive technology. Methods： Retrospectively analyzed 3506 pregnancies cases after ART. Results： Whether spontaneous pregnancy reductions occurred are in relation to the quality of embryos transferred. The risk of preterm delivery and low - birth - weight newborn would improve after spontaneous pregnancy reductions arisen. And the increased risk of adverse obstetric outcome would display if the reductions took place later. Conclusion： Single excellent embryos transfer may be the capable measure to avoid multiple pregnancies and spontaneous pregnancy reductions.