摘要
由于Mg^2+具有拮抗N-甲基-天门冬氨酸(N-methyl-D-aspartment,NMDA)受体,抑制运动神经末梢乙酰胆碱和肾上腺髓质及交感能神经末梢肾上腺素等介质的释放等作用,常用以辅助全身麻醉、术后镇痛等,可明显减少麻醉镇痛药的消耗。
Magnesium has the potential of analgesia via antagonizing the N-methyl-D asparate (NMDA) receptors and inhibiting acetylcholine release from motor nerve terminal and catecholamine release from adrenal medulla and adrenergic nerve ending. Therefore magnesium sulfate may, as an adjuvant for general anesthesia and postoperative analgesia, strengthen the effects of anesthetics, anal - gesics and muscle relaxants, reducing the consumption of these agents.
出处
《国际麻醉学与复苏杂志》
CAS
2010年第2期142-144,I0001,共4页
International Journal of Anesthesiology and Resuscitation
关键词
全身麻醉
术后镇痛
硫酸镁
General anesthesia
Postoperative analgesia
Magnesium sulfate