摘要
采用双波长分光光度法测定复方磺胺间甲氧嘧啶钠注射液中两主药的含量,磺胺间甲氧嘧啶钠的测定波长为262 nm,参比波长为303.5 nm;甲氧苄啶的测定波长为288 nm。磺胺间甲氧嘧啶钠和甲氧苄啶平均回收率分别为98.30%和97.09%。本法操作简便、快速、准确可靠,适用于同时检测复方磺胺间甲氧嘧啶钠注射液中磺胺间甲氧嘧啶钠和甲氧苄啶的含量。
The DW-spectrophotometry has been developed to determine sulfamonomethoxine sodium and trimethoprim in compound sulfamonomethoxine sodium injection,262 nm as determining wavelength of sulfamonomethoxine sodium,303.5 nm as reference wavelength of sulfamonomethoxine sodium,288 nm as determining wavelength of trimethoprim.The average recovery rate of sulfamonomethoxine sodium and trimethoprim were 98.30% and 97.09% respectively.The method was accurate and feasible and can be used for simultaneous determination of sulfamonomethoxine sodium and trimethoprim in compound sulfamonomethoxine sodium injection.
出处
《西北农业学报》
CAS
CSCD
北大核心
2010年第4期21-23,共3页
Acta Agriculturae Boreali-occidentalis Sinica
基金
河南省教育厅自然科学研究项目(2009B230011)
