儿童泌尿系感染的病原学分析

Study on Pathogens of Urinary Tract Infection in Children

探讨目前儿童泌尿系感染病原体的变化趋势,为临床治疗提供实验依据。分析2008年1月至2009年10月住院治疗的357例尿细菌培养、支原体体外培养、衣原体检测阳性的泌尿系感染患儿病原体的分布情况。结果显示,尿细菌培养和支原体体外培养、衣原体检测前未应用过抗生素的患儿其阳性率为82.2%,而应用过抗生素的患儿其阳性率为31.8%,两者相比具有统计学意义(P<0.01)。在检测的357例阳性标本中,革兰阴性杆菌占74.7%,其中以大肠埃希菌为主,占46.2%;革兰阳性球菌占14.8%,其中肠球菌占10.9%;真菌占3.1%,支原体占4.8%,衣原体占2.5%。临床要密切关注儿童泌尿系感染病原体的分布变迁情况,以便于为临床的诊断和治疗提供可靠的实验依据。

In order to investigate the trend of pathogens in children with urinary tract infection （UTI） and provide experimental data for clinical therapy.The distribution of pathogens 357 urine bacteria culture,Mycoplasma culture in vitro,and Chlamydia detection positive hospitalized children with UTI from January 2008 to October 2009 were analyzed.The positive rate of the above-mentioned tests in children patients who had never used antibiotics before the tests was 82.2%.However,those who had used antibiotics prior to the tests was 31.8%.The comparison of both was statistically significant （P0.01）.Among 357 positive samples,gram-negative bacilli accounted for 74.7%,mainly E.coli （46.2%）;gram-positive Cocci 14.8% （with 10.9% of Enterococcus）;fungi 3.1%;Mycoplasma 4.8%,and Chlamydia 2.5%.The distribution changes of pathogens in UTI children should be closely monitored by clinicians in order to provide experimental foundation for diagnosis and therapy.