N,N′-双(2-氨丙基)草酰胺合铜的Cu(Ⅱ)-Fe(Ⅱ)双核配合物的合成、磁性及生物活性

SYNTHESIS, MAGNETISM AND ANTIBACTERIAL ACTIVITY OF μ_OXAMIDO HETEROBINUCLEAR COPPER(II)_IRON(II) COMPLEXES

合成和表征了两种含草酰胺桥的新型异双核配合物［Ｃｕ（ｏｘａｐ）Ｆｅ（ｔｍｅｎ）２］ＳＯ４（ａ）和［Ｃｕ（ｏｘａｐ）Ｆｅ（Ｐｈ２＿ｐｈｅｎ）２］ＳＯ４（ｂ）．其中，ｔｍｅｎ和Ｐｈ２＿ｐｈｅｎ分别代表Ｎ，Ｎ，Ｎ′，Ｎ′－四甲基乙二胺和４，７－二苯基１，１０－邻菲罗啉；ｏｘａｐ代表Ｎ，Ｎ′－双（２－氨丙基）草酰胺根阴离子．测定了配合物（ａ）的变温磁化率（４～３００Ｋ）并用最小二乘法和从自旋哈密顿算符（Ｈ∧＝－２ＪＳ１∧·Ｓ２∧－ＤＳｚ１∧２）导出的磁方程拟合，求得交换参数Ｊ＝－５８．６２ｃｍ－１，表明Ｃｕ（Ⅱ）＿Ｆｅ（Ⅱ）双核配合物中金属离子间有中等强度的反铁磁超交换作用．研究了配合物的生物活性，发现两个双核配合物均具有一定的杀菌作用．

Two new μ_oxamido heterobinuclear complexes [Cu(oxap)Fe(tmen) 2]SO 4 (a) and [Cu(oxap)Fe(Ph 2_phen) 2]SO 4 (b) have been synthesized and characterized, where tmen and Ph 2_phen stand for N,N,N′,N′_tetramethylenediamine and 4,7_diphenyl_1,10_phenanthroline, respectively; oxap represents N,N′_bis(2_aminopropyl)oxamido dianion. The temperature dependence of magnetic susceptibilities of the complex (a) has been measured over the range 4～300 K, and the observed data were successfully simulated by the equation based on the spin Hamiltonian, H∧=-2J S 1 ∧· S 2 ∧-D S z1 ∧ 2, giving the exchange integral J=-58.62 cm -1 . The results are commensurate with moderately strong antiferromagnetic superexchange interactions between the metal ions. The antibacterial activity of the complexes were also examined.