KF/Al_2O_3催化1,2,3-苯并三唑N-烷基化

N Alkylation of 1,2,3 Benzotriazole Catalyzed by KF Alumina

研究了用固体碱ＫＦ／Ａｌ２Ｏ３为缚酸剂，ＤＭＦ为溶剂，以卤代烃为烷基化剂实现１，２，３－苯并三唑Ｎ－烷基化反应．不同的卤代烃，得到不同比例Ｎ１及Ｎ２烷基化产物，烷基化产率在５７％～９５％之间．

N Alkylation of 1,2,3 benzotriazole catalyzed by KF/Al 2O 3 was studied.Be nzotriazole reacted with alkyl halides on KF/Al 2O 3 in DMF at 30 ℃ for 1 h, giving N 1 and N 2 substituted benzotriazoles in yield of 57%～95%.