垂体后叶素和止血合剂对支气管扩张症大咯血止血效果分析

Analysis of curative efficacy on treatment for great volume haemoptysis induced by bronchiectasis with pituitrium and hemostatic mixture

目的：探讨垂体后叶素（ＰＴＴ）和止血合剂（ＨＴＭ）治疗支气管扩张症大咯血的疗效、药理作用、用法、用量及疗程。方法：１１５例支气管扩张症大咯血患者随机分为２组，分别用ＰＴＴ及ＰＴＴ加ＨＴＭ治疗（前者６６例，后者４９例）。结果：ＰＴＴ加ＨＴＭ治疗组的完全止血时间〔（４．１０±１．７９）ｄ〕和ＰＴＴ的平均日剂量〔（２６．５１±５．４４）Ｕ〕均明显低于单用ＰＴＴ治疗组完全止血时间〔（５．７０±２．１５）ｄ〕和ＰＴＴ平均日剂量〔（３３．４４±５．３７）Ｕ〕，２组比较差异非常显著（Ｐ均＜０．００１）。结论：ＰＴＴ加ＨＴＭ治疗大咯血能提高疗效，缩短疗程。

Objective:To investigate the efficacy,pharmacologic actions,using method,doses and course on treatment for great volume haemoptysis induced by bronchiectasis with pituitrium (PTT) and hemostatic mixture (HTM).Methods:115 cases with great volume haemoptysis induced by bronchiectasis were randomly divided into two groups,who were treated with PTT( n =66) or PTT plus HTM( n =49) respectively.Results:In PTT plus HTM group the fully hemostatic time (4 10±1 79)d and the average dosage of PTT (26 51±5 44)U per day were significantly lower than those (5 70±2 15)d and (33 44±5 37)U respectively in PTT group.In comparison between two groups the difference was significant (all P <0 001).Conclusions:The treatment for great volume haemoptysis with PTT plus HTM can enhance curative effects,shorten therapeutic course,and decrease dosage and side effects of PTT.