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自噬在肝癌中的表达及相关机制研究进展 被引量:13

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摘要 自噬是广泛存在于真核细胞生物中的一种溶酶体依赖性的降解系统,它通过降解长寿命蛋白和破损的细胞器而在细胞中发挥一系列生物功能,这对保持细胞内环境的稳定有很大的帮助。但在许多生理及病理应激情况下(诸如营养缺乏、内质网应激等)自噬会被过分激活而导致细胞的死亡,这种死亡方式被称为Ⅱ型程序性细胞死亡,又称自噬性细胞死亡。
出处 《中华实验外科杂志》 CAS CSCD 北大核心 2010年第5期679-680,共2页 Chinese Journal of Experimental Surgery
基金 国家自然科学基金资助项目(30872511) 上海市青年科技启明星计划资助项目(08QA14047) 上海慈善癌症研究基金资助项目
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参考文献25

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二级参考文献7

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