脑梗死患者颈动脉粥样硬化与血尿酸的关系

Relationship between the Level of Plasma Uric Acidand Carotid Atherosclerosis in Patients with Cerebral Infarction

目的:探讨尿酸与颈动脉粥样硬化的关系。方法:对住院的385例脑梗死患者行颈动脉彩超检查,根据内-中膜厚度结果将患者分为正常、硬化/斑块、狭窄3组。结果:不同颈动脉粥样硬化性损害组的血尿酸均高于正常组;随着血尿酸水平的升高,颈动脉粥样硬化的危险度增加。结论:高尿酸血症可能是颈动脉粥样硬化的一个独立危险因素。

Objective： To investigate the relationship between the plasma level of uric acid and the atherosclerosis impairment of carotid. Methods： After the carotid intima-media thickness （IMT） been measured by color Doppler ultrasonography in the in-patients with cerebral infarction, 385 patients were divided into three different groups, i.e., normal, hardening/plaque, and narrow group, based on the ultrasound results. Results： The plasma level of the uric acid was higher in the different carotid-atherosclerosis groups than that in the normal group, and the risk of carotid atherosclerosis was increased with elevated plasma level of uric acid. Conclusion： Those results suggested that hyperuricemia may be an independent risk factor of carotid atherosclerosis.