代谢综合征合并急性脑卒中135例临床分析

Clinical analysis of 135 cases of acute stroke with metabolic syndrome

目的探讨代谢综合征（MS）合并急性脑卒中的临床特征及预后。方法对脑CT或MRI证实的MS合并急性脑卒中患者135例和同期非MS脑卒中患者195例的临床资料进行分析比较。结果脑梗死MS组占92．6％，非MS组占84．6％；近期病死率MS组为24．4％，非MS组为9．7％；MS组肺部感染、呼吸衰竭、心力衰竭、肾功能衰竭发生概率较非MS组升高，脑疝与消化道出血发生率差异无统计学意义（P〉0．05）。结论MS合并急性脑卒中以急性脑梗死多见，并发症多，近期病死率高。

Objective To investigate the clinical characteristics and the prognosis of acute stroke with metabolic syndrome. Methods 135 acute stroke patients with metabolic syndrome were recruited, and 195 acute stroke patients without metabolic syndrome were selected as controls. Results The prevalence of cerebral infarction was significantly increased in stroke patients in MS group than those in control group. The prognosis of patients in control group（ mortality 24.4% ） were better than the stroke patients in MS group（ mortality 9.7% ）. There was significant difference in severe complication,including pulmonary infection, respiratory failure, heart failure, arrythmias and kidney failure between MS group and control group. However, there was no significant difference in onset of cerebral hernia and gastrointestinal hemorrhage between the two groups. Conclusions The prevalence of cerebral infarction remarkably increased in stroke patients with metabolic syndrome. The mortality and incidence of complication in stroke with metabolic syndrome is higher.