广东省惠州地区冠心病危险因素的调查研究

Investigation of risk factors of coronary heart disease in Huizhou

目的分析惠州地区体检人群冠心病（CHD）的危险因素。方法以970例体检对象中检出的85例CHD患者为研究对象，对6项CHD的危险因素进行分析。结果体检970例中，诊断CHD（冠心病组）85例（8．8％），非CHD组（对照组）338例（34．8％），健康者547洌（56．4％）；85例CHD患者60～69岁、70-79岁的CHD患病率明显高于50—59岁（x^2=6．78，X^2=7．02，P均〈0．01）；肥胖、吸烟、大量饮酒、高血压和血脂异常的比例显著高于对照组（（t=2．71，t=2．803，t=2．875，t=2．841，t=2．901，均P〈0．01）；85例CHD患者集聚指数≥1％以上的占92．8％，集聚指数≥3％以上占41．2％；CHD与TC（r=0．28，P〈0．001）、TC（r=0．23，P〈0．001）、SBP（r=0．14，P=0．011）水平显著正相关。结论血脂异常、高血压、肥胖、吸烟、大量饮酒是惠州地区冠心病显著的危险因素。

Objective To analyze the risk factors of coronary heart disease（CHD） by health examination in Huizhou. Methods A total of 85 patients withCHD,were chosen from 970 health check-up subjects as research cases. The roles of 6 risk factors of CHD were analyzed. Results 970 examination, amomg the CHD group were 85 cases （ 8.8% ） , non-CHD group（ control group） 338 eases （ 34.8% ） , normal healthy individuals 547 eases （ 56.4% ） respectively ;The age of 60-year-old ,70-year-old were significantly higher than 50 years in CHD（x2 = 6.78, X^2 = 7.02, P 〈 0. 01 ） ;The prevalence of obesity ,smoking,over-drinking,hypertension and dyslipidemia in CHD group were high- er than that in control group（t =2.71 ,t =2. 803,t =2. 875 ,t =2. 841 ,t =2. 901 ,all P 〈0.01 ） ;The index of crowding index ≥ 1 for 92.8%, ≥ 3% for 41.2% in 85 cases with CHD ; Analysis showed that coronary heart disease and TG （ r = 0.28, P 〈 0.001 ） , TC （ r = 0.23, P 〈 0.001 ） , SBP （ r = 0.14, P = 0.011 ） were significantly positively correlated. Conclusions Dyslipidemia ,hypertension ,obesity ,smoking,over-drinking are the remarkable risk factors of CHD in Hui Zhou