未足月胎膜早破730例临床分析

A clinical study on 730 cases with preterm premature rupture of membranes

目的 探讨未足月胎膜早破的临床表现和治疗方式。方法回顾性分析未足月胎膜早破患者730例的临床资料，总结其临床特征及围产结局。结果未足月胎膜早破的发病率为2．68％；发生未足月胎膜早破的相关因素依次是感染、子宫张力高、胎位异常等；围产儿并发症以早产、胎儿窘迫、胎儿呼吸窘迫综合征为主；围产儿结局与孕周直接相关。结论针对未足月胎膜早破发生的相关因素采取相应的临床处理，加强孕期保健，综合治疗，可减少母儿病率，改善早产儿预后。

Objective To explore the clinical characteristics and treatment strategies in preterm premature rupture of membranes. Methods The clinical data of 730 cases with preterm premature rupture of membranes from January 2005 to December 2009 in our hospital were retrospectively analyzed. The characteristics and perinatal outcomes were summarized. Results The incidence rate of preterm premature rupture of membranes was 2.68 %. The relative factors developing preterm premature rupture of membranes were in turn infection, high tension of uterus and abnormal fetal position. The perinatal complications were mainly preterm, fetal distress and RDS. The perinatal outcomes were directly related to the gestational weeks. Conclusion According to the relative factors leading to preterm premature rupture of membranes,adopting the relative clinical treatment,strengthening the gestational health and comprehensive treatment may reduce the morbidity of maternal and newborn and improve the prognosis of preterm neonates.