婴儿肝炎综合征42例临床分析

Clinical analysis of 42 cases with infantile hepatitis syndrome

目的总结婴儿肝炎综合征的病因、临床表现、治疗与预后。方法对42例肝炎综合征患儿临床表现进行分析，检测血巨细胞病毒、乙型肝炎病毒、细菌培养及相关生化指标。结果42例均有肝功能损害及黄疸，血巨细胞病毒感染20例，乙型肝炎病毒感染6例，虮培养有葡萄球菌生长3例，经中西医综合治疗，治愈率95％（37／39），3例失访。结论婴儿肝炎综合征的主要病因为巨细胞病毒、乙型肝炎病毒、细菌感染，临床表现主要为肝功能损害、黄疸，经综合治疗预后较好。

Objective To summarize the etiologies of infant hepatitis syndrome,clinical presentation,treatment and prognosis. Methods The clinical symptoms of 42 cases with infantile hepatitis syndrome were observed and the blood cytomegalovirus,hepatitis B virus, cell cuhure and a series of related biochemical parameters were exaintried. Results All of patients＇liver have been damaged and have jaundice,blood CMV infection accounted for 48% （20/42） , hepatitis B virus, accounting for 14% （6/42） , blood cultures have staphylococcus up to 7% （3/42）. After combining Chinese and Western medicine treatment,the sufferers restore to health,cure rate up to 95% （37/39） ,3 cases were lost. Conclusion The infant hepatitis syndrome originate from the infections of the blood cytomegalovirns, hepatitis B virus and bacterial infection,whose clinical manifestations are infant liver damaged and jaundice. We have a better prognosis on infantile hepatitis syndrome and the resuh of combining Chinese and Western medicine treatment is good.