无创机械通气治疗慢性阻塞性肺病合并呼吸衰竭疗效观察

Non-invasive mechanical ventilation in the treatment of chronic obstructive pulmonary disease with re- spiratory failure Efficacy

目的探讨双水平气道正压无创通气（BIPAP）对慢性阻塞性肺病（COPD）合并呼吸衰竭的冶疗价值。方法对COPD合并Ⅱ型呼吸衰竭患者47例行双水平气道正压无创通气（BIPAP），记录治疗前，上机后2h、1d、3d的pH、PaO2、PaCO2、SPO2变化。结果所有患者经过双水平气道正压无创通气后，临床症状有明显好转，治疗后血气分析中的pH、PaO2、PaCO2、SPO2较治疗前有明显改善（P〈0．05）。结论双水平气道正压无创通气（BIPAP）对慢性阻塞性肺病（COPD）合并呼吸衰竭患者疗效显著。

Objective To explore the hi-level positive airway pressure non-invasive ventilation （BI- PAP） for chronic obstructive pulmonary disease （COPD）with respiratory failure, the value of the cure. Methods COPD patients with type ]] respiratory failure 47 regular bi-level positive airway pressure non-invasive venti- lation（ BIPAP）, recorded the change before treatment,on the plane two hours after one day, three days PH, PaO2, PaCO2, SPO2 change. Results All patients through the bi-level positive airway pressure non-invasive ventilation, the clinical symptoms significantly improved after treatment, blood gas analysis The PH, PaO2, PaCO2 , SPO2 a significant improvement compared with before treatment （ P 〈 0. 05 ）. Conclusion The hi-level positive airway pressure non-invasive ventilation（BIPAP） for chronic obstructive pulmonary disease （COPD）with respiratory failure has a significant effect.