幽门螺杆菌感染与过敏性紫癜相关性研究

Study the allergic purpura association with Helicobacter pylori infection

目的研究幽门螺杆感染与过敏性紫癜的相关性并指导治疗。方法对2007年12月至2009年12月在本科治疗的120例HSP患者进行了HPIgG抗体检查、并将血Hp—IgG阳性的患者随机分为2组，A组在常规治疗的基础上给与抗Hp治疗，B组仅用常规治疗，对治愈患者随访6个月。结果120例过敏性紫癜患者血Hp-IgG阳性81例（67．5％），Hp—IgG阳性的HSP患者在常规治疗的基础上给与抗Hp治疗，有效率高，且复发率低。结论幽门螺杆菌感染是过敏性紫癜发病的重要因素之一，抗Hp治疗有利于HSP的康复。

Objective To study the relationship between allergic purpura and Helicobacter pylori in- fection and direct therapy. Methods From December 2007 to December 2009 120 cases at the undergraduate treated of HSP patients had HP-IgG antibody been tested, and serum Hp-IgG-positive patients were randomly divided into two groups, A group on the basis of conventional therapy to give anti-Hp therapy, B group only con- ventional treatment, cured patients were followed up for 6 months. Results 120 case with The percentage of Hp- IgG-positive is 67.5%, Hp-IgG-positive HSP patients given conventional therapy on the basis of anti-Hp therapy, there are high efficiency and low recurrence rate. Conclusion Helicobacter pylori infection in the pathogen- esis of allergic purpura is one important factor, anti-HP therapy is conducive to the rehabilitation of HSP.