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血清肿瘤标志物动态检测在乳腺癌早期诊断和复发转移中的价值 被引量：1

The Significance of dynamic detection for the serum tumor marker in breast cancer with recurrence and metastasis
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摘要 目的探讨血清肿瘤标志物动态检测在乳腺癌早期诊断和监控复发转移中的价值。方法采用化学发光法检测187例乳腺癌组患者血清CA15-3、CA125和CEA的水平，并与20例良性病变组患者对照，分析与乳腺癌临床分期和复发转移的关系。结果乳腺癌患者CA15-3、CA125和CEA水平Ⅲ、Ⅳ期明显高于良性对照组和Ⅰ、Ⅱ期组（P〈0．01）；淋巴结转移组、复发组与无转移组、无复发组差异有统计学意义（P〈0．05）。结论CA15-3、CA125和CEA与复发转移相关，血清学动态检测是乳腺癌早期诊断和监控复发转移的较好指标。 Objective To study the Significance of dynamic detection for the serum tumor marker in breast cancer with recurrence and metastasis. Methods The serum from 187 patients with breast cancer was collected and tumor markers CA15-3, CA125and CEA were detected with CLIA method. Results CA15-3, CA125 and CEA had a positive correlation with the clinical stage （ P 〈 0. 01 ） and lymphnode metastas and Showed significantly higher in the group of recurence and metastasis than no recurrence and metastasis （ P 〈 0. 05 ）. Conclusion The positive rates of CAIS-3, CA125 and CEA had a significantly correlation with recurrence and metastasis. The dynamic detection of CEA and CA153 are better prewarning markers for monitoring their recurrence and metastasis of breast cancer.
作者 徐风亮 张荣华 吴鹏 王刚平
机构地区 济宁医学院附属日照市人民医院临床检验科 济宁医学院附属日照市人民医院普外科 济宁医学院附属日照市人民医院病理科
出处 《中国临床实用医学》 2010年第5期81-82,共2页 China Clinical Practical Medicine
关键词 乳腺肿瘤 血液 肿瘤标志物 早期诊断 Breastneoplasms Blood Tumor marker Early diagnosis
分类号 R737.9 [医药卫生—肿瘤]
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参考文献4

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二级参考文献9

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共引文献14

同被引文献31

  • 1郑航,罗荣城.TPS、CA-153和CEA联合检测对乳腺癌的诊断价值[J].第一军医大学学报,2005,25(10):1293-1294. 被引量：46
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中国临床实用医学
2010年 第5期

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