两种方法用于人工流产镇痛效果的临床比较研究

Comparison of clinical analgesic effects of two methods in artificial abortion

目的比较盐酸哌替啶、异丙嗪、芬太尼联合利多卡因（试验组）与丙}白酚联合芬太尼（对照组）用于人工流产术中的临床镇痛效果。方法将480例自愿选择人工流产术的早孕妇女分为试验组与对照组，每组各240例，观察两组的镇痛效果、术中出血量，呼吸、循环抑制情况，人工流产综合征发生率及药物副反应等。结果两组均取得良好的镇痛效果，但对照组呼吸、循环抑制的发生率明显高于试验组。结论盐酸哌替啶、异丙嗪、芬太尼联合利多卡因用于人工流产术中镇痛效果好，且较丙泊酚联合芬太尼更安全。

Objective To compare clinical analgesic effects of administration of combination of pethi- dine, promethazine, fentanyl and lidocaine with combination of propofol and fentanyl in artificial abortion. Meth- ods 480 pregnant women undertook artificial abortion were divided equally into two groups. Analgesic effects, hemorrhage volume during operation, respiration and circulation depression, incidence of artificial abortion syn- drome and side-effects of drugs were observed for each group. Results Good analgesic effects were achieved in both groups. However, incidence of respiration and circulation depression was much higher in control group. Conclusion Administration of combination of pethidine, promethazine, fentanyl and lidocaine has good analgesic effects in artificial abortion. It＇ s also safer than administration of combination of vrovofol and fentanvl.