液基细胞学筛查宫颈癌临床研究应用

Liquid-based cytology screening for cervical cancer of clinical research and application

目的将宫颈液基细胞学与巴氏细胞学染色进行比较研究，评价液基细胞学对宫颈病变筛查的敏感性与临床价值。方法对511例患者经过两种方法进行细胞学分析采用TBS标准，将其结果进行比较分析。结果在液基细胞学与巴氏细胞学两种方法均见异常的患者中，以组织学活检做对照，液基细胞学阳性率明显高于巴氏细胞学。结论液基细胞学与巴氏细胞学诊断相比，具有更高的敏感性，能提高检出率，从而使患者得到早发现、早诊断及早治疗。

Objective To make a comparative study between the Liquid-based cervical cytology and the Papanicolaou stain cytology, to evaluate the sensitivity of Liquid-based cytology to cervical pathology screen- ing and its clinical value. Methods To apply the cytological analysis on 511 patients in two ways by using the TBS standards to let the two results be analyzed and compared with each other. Results Among the patients who are abnormal both in the Liquid-based cytology and the Papanicolaou cytology, the positive rate of the Liquid-based cytology is obviously higher than the Papanicolaou cytology＇ s, compared to the tissue biopsy. Conclusion Liquid-based cytology has a higher sensitivity compared with Papanicolaou cytology. It be can able to enhance the rate of detecting, thus achieve the goal of early detection, diagnosis and treatment.