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非小细胞肺癌脑转移调强放射治疗13例

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摘要 目的通过观察调强放射疗法(IMRT)治疗非小细胞肺癌(NSCLC)脑转移疗效,探讨其临床意义。方法2008年5月至2009年11月采用共面5野同步补量(SIB)IMRT治疗13例NSCLC脑转移患者,全脑剂量[计划靶区(PTV)一临床靶区(CTV)]2Gy/次,D,40Gy,脑转移灶[PTV-肿瘤靶区(GTV)12.5~2.8Gy/次,D,50~56Gy,均为5次/周,共20次。同步结束,95%的等剂量曲线包括靶区,放疗结束后行脑部CT或MRI评价疗效。结果CR为4例,PR为8例,SD为1例。治疗有效率92.3%(12/13)。结论全脑及脑转移灶IMRT治疗NSCLC脑转移有较高的局控率,不良反应轻,值得推广应用。
出处 《肿瘤研究与临床》 CAS 2010年第4期271-272,共2页 Cancer Research and Clinic
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