肺炎链球菌大环内酯药物耐药性及耐药基因erm、mef的检测
被引量:10
摘要
肺炎链球菌是引起呼吸道感染的常见菌。近年来,耐药型肺炎链球菌出现迅猛,在我国和众多亚洲国家尤为明显。肺炎链球菌对大环内酯类抗生素的耐药率迅速增加,目前已成为一个全球性问题。其中对红霉素的耐药性已成为一个严重的现象。
出处
《中华传染病杂志》
CAS
CSCD
北大核心
2010年第3期174-177,共4页
Chinese Journal of Infectious Diseases
参考文献11
-
1Adam D.Global antibiotic resistance in Streptococcus pneumoniae.J Antimicrob Chemother,2002,50 Suppl:S1-5.
-
2Jacobs MR,Felmingham D,Appelbaum PC,et al.The Alexander Project 1998-2000:susceptibility of pathogens isolated from community-acquired respiratory tract infection to commonly used antimicrobial agents.J Antimicrob Chemother,2003,52,229-246.
-
3National Committee for Clinical Laboratory Standards.Performance standards for antimicrobial susceptibility testing,9th informational supplement.Wayne,Pa:NCCLS,2002M100-S12.
-
4Sutcliffe J,Grebe T,Tait-Kamradt A,et al.Detection of erythromycin-resistant determinants by PCR.Antimicrob Agents Chemother,1996,40:2562-2566.
-
5Sepp(a)la H,Skurnik M,Soini H,et al.A novel erythromycin resistance methylase gene (erm TR) in Streptococcus pyogenes.Antimicrob Agents Chemother,1998,42:257-262.
-
6Del Grosso M,Iannelli F,Messina C,et al.Macrolide efflux genes mef(A) and mef(E) are carried by different genetic elements in Streptococcus pneumoniae.J Clin Microbiol,2002,40:774-778.
-
7Felmingham D,Reinert RR,Hirakata Y,et al.Increasing prevalence of antimicrobial resistance among isolates of Streptococcus pneumoniae from the PROTEKT surveillance study,and compatative in vitro activity of the ketolide,telithromycin.J Antimicrob Chemother,2002,50 Suppl 1:S25-37.
-
8姚开虎,王立波,赵根明,郑跃杰,邓力,赵瑞珍,邓秋莲,胡英惠,俞桑洁,沈叙庄,杨永弘.四家儿童医院住院肺炎病例肺炎链球菌分离株的耐药性监测[J].中国当代儿科杂志,2008,10(3):275-279. 被引量:58
-
9Tait-Kamradt A,Clancy J,Cronan M,et al.mefE is necessary for the erythromycin-resistant M phenotype in Streptococcus pneumoniae.Antimicrob Agents Chemother,1997,41:2251-2255.
-
10Song JH,Chang HH,Suh JY,et al.Macrolide resistance and genotypic characterization of Streptococcus pneumoniae in Asian countries:a study of the Asian Network for Surveillance of Resistant Pathogens (ANSORP).J Antimicrob Chemother,2004,53:457-463.
二级参考文献24
-
1张璟,孙自镛.儿童鼻咽部肺炎链球菌携带株研究[J].中国感染与化疗杂志,2007,7(2):96-100. 被引量:8
-
2National Committee for Clinical Laboratory Standards.Performance standards for antimicrobial susceptibility testing.Pennsylvania:NCCLS,2002.M100-S12.
-
3Statement 1996 CA-SFM Zone sizes and MIC breakpoints for non-fastidious organisms.Clin Microbiol Infect,1996,2 Suppl 1:S46.
-
4Morosini MI,Canton R,Loza E,et al.In vitro activity of telithromycin against Spanish Streptococcus pneumoniae isolates with characterized macrolide resistance mechanisms.Antimicrob Agents Chemother,2001,45:2427-2431.
-
5Sutcliffe J,Grebe T,Tait-Kamradt A,et al.Detection of erythromycin-resistant determinants by PCR.Antimicrob Agents Chemother,1996,40:2562-2566.
-
6Kataja J,Huovinen P,Skurnik M,et al.Erythromycin resistance genes in group A streptococci in Finland.The Finnish Study Group for Antimicrobial Resistance.Antimicrob Agents Chemother,1999,43:48-52.
-
7Granizo JJ,Aguilar L,Casal J,et al.Streptococcus pneumoniae resistance to erythromycin and penicillin in relation to macrolide and beta-lactam consumption in Spain (1979-1997).J Antimicrob Chemother,2000,46:767-773.
-
8Nishijima T,Saito Y,Aoki A,et al.Distribution of mefE and ermB genes in macrolide-resistant strains of Streptococcus pneumoniae and their variable susceptibility to various antibiotics.J Antimicrob Chemother,1999,43:637-643.
-
9Yao K, Shen X, Yu S, Lu Q, Deng L, Ye Q, et al. Antimicrobial resistance and serotypes of nasopharyngeal strains of Streptococcus pneumoniae in Chinese children with acute respiratory infections [JJ. J Int Med Res, 2007,35(2) :253-267.
-
10Clinical and Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing; 16th informational supplement. M100-S16 [M]. Wayne, PA: Clinical and Laboratory Standards Institute, 2006, 134-136.
共引文献115
-
1潘树根,杨银梅,郭海波.肺炎链球菌对大环内酯-林可酰胺-链阳菌素的耐药监测及耐药机制研究[J].分子诊断与治疗杂志,2009,1(4):238-240. 被引量:2
-
2佘丹阳,刘又宁.不同国家、地区细菌耐药性差别与抗感染治疗对策[J].中华医学杂志,2004,84(22):1916-1918. 被引量:15
-
3李冬,王爽,陈佰义.大环内酯类耐药肺炎链球菌及其临床意义[J].中华内科杂志,2005,40(1):70-72. 被引量:9
-
4陈修全,方艳萍.氧氟沙星治疗社区获得性肺炎90例临床观察[J].临床肺科杂志,2005,10(1):65-66.
-
5沈叙庄,杨慧.肺炎链球菌对大环内酯类抗生素耐药的研究进展[J].实用医院临床杂志,2005,2(3):12-14. 被引量:17
-
6朱胜金,杨丹.肺炎链球菌耐药基因及其分子生物学检测[J].贵州医药,2011,35(1):82-84. 被引量:7
-
7杨慧,杨永弘,Elisabet Nielsen,俞桑洁,袁林,王咏红,沈叙庄.肺炎链球菌耐药基因ermB、mefA、tetM与转座子整合酶基因intTn的检测[J].中华微生物学和免疫学杂志,2005,25(8):677-682. 被引量:19
-
8刘又宁,佘丹阳.我国下呼吸道感染致病原的构成、耐药特点及治疗策略[J].中国新药杂志,2005,14(9):1117-1122. 被引量:12
-
9陈亚红,赵鸣武.大环内酯类抗生素在社区获得性肺炎治疗中的临床评价[J].中国医院用药评价与分析,2005,5(5):267-269. 被引量:12
-
10莫建坤,李明友,黎永新,雷达.肺炎链球菌对抗生素耐药机制基因研究进展[J].国际医药卫生导报,2005,11(24):115-116. 被引量:2
同被引文献101
-
1吴佳学.青霉素敏感和耐药肺炎链球菌耐药性比较及基因型分析[J].中华临床感染病杂志,2011,4(3). 被引量:10
-
2杨慧,杨永弘,Elisabet Nielsen,俞桑洁,袁林,王咏红,沈叙庄.肺炎链球菌耐药基因ermB、mefA、tetM与转座子整合酶基因intTn的检测[J].中华微生物学和免疫学杂志,2005,25(8):677-682. 被引量:19
-
3张春,陆晓彤.儿童专科医院临床病原菌分布与抗菌药物耐药分析[J].中华医院感染学杂志,2006,16(4):434-437. 被引量:24
-
4张建华,丁云芳,糜祖煌,秦玲,盛锦云,赵根明.儿童肺炎链球菌分离株红霉素耐药性与相关耐药基因研究[J].临床儿科杂志,2006,24(7):561-563. 被引量:9
-
5郑亚芬,韩小雅,承晓京,宋海英.肺炎链球菌新生儿分离株转座酶基因遗传标记的研究[J].中国人兽共患病学报,2007,23(5):493-494. 被引量:8
-
6胡亚美 江载芳.诸福棠实用儿科学[M]第7版[M].北京:人民卫生出版社,2002.1514.
-
7Werao AM, Murdoch DR. Medical microbiology : laboratorydiagnosis of invasive pneumococcal disease [J]. Clin InfectDis, 2008,46(6):926-932.
-
8O'Brien KL, Wolfson LJ,Watt JP,et al. Burden of diseasecaused by Streptococcus pneumoniae in children youngerthan 5 years: global estimates [J]. Lancet, 2009, 374(9693):893-902.
-
9van der Poll T, Opal SM. Pathogenesis, treatment, and pre-vention of pneumococcal pneumonia [J]. Lancet, 2009, 374(9700):1543-1556.
-
10Cardozo DM,Nascimento-Carvalho CM,Andrade AL,et al.Prevalence and risk factors for nasopharyngeal carriage ofStreptococcus pneumoniae among adolescents [J]. J Med Mi-crobiol ,2008,57(Pt2) :185-189.
引证文献10
-
1孟爱华,张帅,张淑明,胥振阳.肺炎链球菌药物敏感性分析[J].中国临床医生杂志,2014,42(3):36-37. 被引量:8
-
2张小龙,罗征秀,符州,罗健,刘恩梅.儿童侵袭性肺炎链球菌病54例临床特点及耐药性分析[J].临床儿科杂志,2014,32(6):555-558. 被引量:21
-
3苏敏,常莉,周伟,母丽媛,旷凌寒.儿童肺炎链球菌脑膜炎的临床特点及耐药性分析[J].中国当代儿科杂志,2015,17(7):706-709. 被引量:7
-
4金亮,李达,王勇雁,陈丹丹,刘辉.234株肺炎链球菌的耐药性分析[J].检验医学,2016,31(7):627-629. 被引量:7
-
5魏楚洪.佛山地区小儿肺炎链球菌临床分布特征及耐药性分析[J].临床合理用药杂志,2017,10(18):83-85. 被引量:5
-
6金亮,赵建宏,时东彦,李志荣,冯军花,温海楠,左江华,苏维,邢欢.2015年河北省53所医院临床分离肺炎链球菌耐药性监测[J].中国感染与化疗杂志,2017,17(6):668-671. 被引量:5
-
7陈静宜,廖飞,冯磊,储从家.玉溪市2014年至2016年儿童肺炎链球菌感染流行情况及耐药性分析[J].昆明医科大学学报,2017,38(11):82-85. 被引量:5
-
8陈静宜,廖飞,冯磊.2016年玉溪市某院儿童下呼吸道感染细菌菌群分布及耐药性分析[J].分子诊断与治疗杂志,2018,10(3):148-152. 被引量:17
-
9韩娇,韩志英.儿童肺炎链球菌耐药性及耐药基因分型研究[J].临床医药文献电子杂志,2018,5(35):195-196. 被引量:2
-
10金亮,李达,王勇雁,陈丹丹,刘辉,郝殿晋,陈宏伟.2012~2016金黄色葡萄球菌和肺炎链球菌分布及耐药趋势分析[J].临床输血与检验,2018,20(1):68-72. 被引量:15
二级引证文献86
-
1丘丹萍,李泰阶,王柏莲,李明强,薛野,覃美香,梁婵.玉林地区住院患者肺炎链球菌感染的流行病学特点[J].热带医学杂志,2023,23(7):1015-1019.
-
2李佳,杨丽.儿童肺炎链球菌肺炎的临床特征及药敏分析[J].世界最新医学信息文摘,2019,0(103):155-155.
-
3邹志平.儿童侵袭性肺炎链球菌病102例临床特征及耐药性分析[J].深圳中西医结合杂志,2015,25(1):188-190. 被引量:7
-
4牛辛元.大环内酯类耐药肺炎链球菌感染的临床与实验室研究进展[J].中国医院用药评价与分析,2015,15(4):556-557. 被引量:2
-
5杨爱君.儿童侵袭性肺炎链球菌感染[J].中国医刊,2015,50(10):27-30. 被引量:2
-
6隆滟丹,唐小飞,张艳,陈晓英.基层医院儿童肺炎链球菌耐药性分析[J].儿科药学杂志,2016,22(4):38-40. 被引量:1
-
7金亮,李达,王勇雁,陈丹丹,刘辉.234株肺炎链球菌的耐药性分析[J].检验医学,2016,31(7):627-629. 被引量:7
-
8孔山,忽胜和,杨新原,赵卫东.98株肺炎链球菌的临床分布及耐药性分析[J].大理大学学报,2016,1(8):62-64. 被引量:1
-
9王荃,武洁,刘珺,董方,姚开虎,申昆玲,钱素云.儿童重症监护病房中侵袭性肺炎链球菌病的临床特点和预后分析[J].中华实用儿科临床杂志,2016,31(18):1400-1404. 被引量:23
-
10简国江,潘庭荣,艾莉莉,陈祥瑞,黄梅.社区获得性小儿支气管肺炎肺炎链球菌药物敏感分析[J].国际检验医学杂志,2016,37(20):2887-2889. 被引量:9
-
1杨永弘.进一步关注儿科抗生素合理应用和细菌耐药[J].中国实用儿科杂志,2010,25(1):1-3. 被引量:27
-
2李智慧.21世纪重要耐药威胁——超广谱β-内酰胺酶的特点和检测[J].口岸卫生控制,2005,10(5):27-30.
-
3王佩倍,庞俊霞,赖宜生.c-Kit激酶抑制剂的研究与开发[J].药学进展,2014,38(7):497-506. 被引量:3
-
4李玉贤,张文娟,尚遂存.黄连素作为抗糖尿病药物的临床应用及优势[J].中国实用医药,2010,5(12):255-257. 被引量:7
-
5冯恩勤,林承仪.诺氟沙星治疗小儿耐药型伤寒41例[J].新药与临床,1990,9(3):166-166. 被引量:4
-
6李平,阎金萍.萘替米星与妥布霉素治疗耐药型下呼吸道细菌感染的比较[J].中国新药与临床杂志,1998,17(3):183-184. 被引量:4
-
7刘继红,陈晓瑜,孟洁,张桂荣.葡萄球菌132株耐药性研究[J].山西医药杂志(下半月),2008,37(5):449-449.
-
8杜小鹏.抗生素的合理使用与公共健康[J].健康向导,2012,18(3):26-27.
-
9聂蔚,唐昊,修清玉.抗菌药物耐药机制和抗感染治疗研究进展[J].中国呼吸与危重监护杂志,2011,10(6):606-610. 被引量:4
-
10贺晓生.补钙,维D有话说[J].家庭医药(快乐养生),2011(2):24-25.