血清PSA、IPSS评分及前列腺体积与勃起功能障碍的关系

Correlation between erectile dysfunction and PSA, IPSS, PV of patients with benign prostate hyperplasia

目的探讨老年前列腺增生患者血清PSA、IPSS症状评分和前列腺体积与勃起功能障碍之间的关系。方法应用IIEF-5国际勃起功能指数问卷表对入选的BPH患者进行阴茎勃起功能障碍评估,以13分为临床诊断分界线,分为A组(≤12分的为性功能较差的BPH组)和B组(≥13分的为性功能较好的BPH组);两组病例均分别进行IPSS评分、经直肠B超前列腺体积和血清PSA值测定。结果本研究共收集病例108例,年龄59～89岁,平均年龄(73.67±5.41),BPH伴发ED的发生率为49.07%。A、B两组之间IPSS评分值分别为(23.23±6.05)、(19.98±7.16),两组比较,差异有统计学意义P<0.05,同时对两组IPSS评分和IIEF评分之间行相关分析得出r=0.115,有一定的相关性。A、B两组前列腺体积测定值分别为(63.19±35.38)ml、(58.91±34.99)ml,两组比较差异无统计学意义(P>0.05)。A、B两组PSA值分别为(5.25±4.48)ng/d1、(4.48±4.46)ng/dl,两组比较差异无统计学意义(P>0.05);同时对IPSS评分与IIEF-5评分行相关分析,r=0.24,显示一定的相关性。结论 BPH患者有很高的ED发生率。血清PSA与前列腺体积测定值和IPSS评分值有明显的相关性,下尿路症状明显的患者ED发生的风险率更高。

Objective To explore the relationship between serum PSA、IPSS scoring and prostate volume（PV） of senile male BPH and ED. Methods Using IIEF-5 International Index （IIEF） for Erectile Function questionnaires, the erectile dysfunction of enrolled patients with BPH was assessed and divide into 2 groups, including group A （clinical diagnostic dividing line ≤12, with weaker sexual function） and group B （clinical diagnostic dividing line ≥13, with better sexual function）. I-PSS, transrectal type-B ultrasound prostate volume and serum PSA of all patients were detected respectively .Results： A total of 108 patients, with a maximum age of 85, minimum age of 59, and an average age of （73.67±5.41）,were enrolled in this trial. The incidence of ED in BPH patients was 49.07%. IPSS score was （23.23±6.05） in Group A and （19.98±7.16） in group B, （P〈0.05）. There was a weak correlation between IPSS scoring and IIEF scoring （r=0.115） in two groups. Prostate volume was 63.19±35.38 （ml） in group A and （58.91±34.99）ml in group B. （P〉 0.05）. Serum PSA was （5.25±4.48） in group A and （4.48±4.46）ng/dl in group B （P〉0.05）. In addition, There was a certain correlation between IIEF-5 score and IPSS score （r=0.24）. Conclusion BPH patients frequently had a high incidence of ED. There was a correlation between serum PSA and IPSS scoring or prostate volume in group A and group B. Patients with severe lower urinary tract symptoms had a higher risk of ED occurrence.