摘要
目的探讨复方玄驹胶囊治疗男性脾肾阳虚少、弱精子症的疗效。方法 2008年6月至2009年3月我院泌尿男科门诊33例不育症患者,给予复方玄驹胶囊口服治疗24周,并分别于治疗第4、8、12、16、20、24周末复诊,接受访视,并做各项检查。观察指标包括:精液常规分析、精子形态学分析、精液、精浆生化检查、生殖激素5项测定。结果治疗24周后,33例患者精子密度、a级精子比例、(a+b)级精子比例及活率均较用药前提高,差异有统计学意义(P<0.05)。33例患者(有3例中度退出)中治愈8例(26.67%),显效2例(6.67%),有效6例(20.00%),其中有2例患者在治疗期间配偶怀孕,总有效率为53.34%。精浆果糖和α-中性糖苷酶均有所提高,而生殖激素指标治疗前后变化不大(P>0.05),结论复方玄驹胶囊治疗脾肾阳虚少、弱精子症患者有较好疗效并具有一定安全性。
Objective To investigate the efficacy of Compound Xuanju Capsule for treating oligoathenospermia due to spleen and kidney Yang deficiency. Methods Between Jun, 2008 and Mar, 2009, 33 male infertile patients in our andrology department were given Compound Xuanju Capsule for a period of 24 weeks and came for followed-up at the 4th, 8th, 12th, 16th, 20th and 24th weekend for receiving clinical examinations and safety evaluation. Observation items include: semen analysis, sperm morphology analysis, seminal plasma biochemical analysis and serum sex hormone. Results After treatment for 24 weeks. The sperm density, sperm motility, a Class and a+b class sperm percentage increased significantly when (P〈0.05). Compared with those before treatment, 2 patients' partners conceived during treating period, the total effective rates was 53.34%.Fructose density and a -glycosidase also increased, but no statistical significance. Serum sex hormone of two groups did not vary before and after treatment(P〉0.05). Conelusion Compound Xuanju Capsule for treating oligoathenospermia due to spleen and kidney Yang deficiency is effective.
出处
《中国男科学杂志》
CAS
CSCD
2010年第4期54-57,共4页
Chinese Journal of Andrology
基金
上海市科委国际合作项目基金(08410701700)
上海市人口和计划生育委员会基金(2007JG06)
关键词
不育
男性
复方玄驹胶囊
脾肾阳虚
infertility, male
Compound Xuanju Capsule
spleen-kidney Yang deficiency