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多囊卵巢综合征合并非酒精性脂肪肝患者的临床特点 被引量:2

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摘要 目的:分析多囊卵巢综合征(PCOS)合并非酒精性脂肪肝(NAFLD)患者的临床特征及其相互关系。方法:回顾性分析24例PCOS并NAFLD患者(研究组)和24例无NAFLD的肥胖PCOS患者(肥胖对照组)及24例无NAFLD的非肥胖PCOS患者(非肥胖对照组)的临床资料、肝肾功能、血脂、葡萄糖耐量试验、空腹胰岛素(FNS)稳态评估法(HOMA-IR)和胰岛素抵抗(IR)的差异。结果:研究组均为中心性肥胖,与肥胖对照组比,IR和代谢综合征发生率高。研究组空腹血糖、FNS、HOMA-IR、甘油三酯、尿酸和丙氨酸氨基转移酶(ALT)高于对照组(P<0.05)。ALT与FNS和HOMA-IR正相关,与总睾酮不相关。结论:NAFLD的PCOS患者以肥胖、高甘油三酯和高尿酸为特点,是胰岛素抵抗的高危人群,更易进展为代谢综合征,肥胖型PCOS应该常规筛查NAFLD。
作者 林芸 邢福祺
出处 《实用医学杂志》 CAS 北大核心 2010年第9期1572-1574,共3页 The Journal of Practical Medicine
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