摘要
肉毒素是由肉毒杆菌分泌的一种神经毒素,肉毒素中毒可导致患者多器官功能障碍。6例患者均为女性,年龄25～55岁,注射肉毒素2～9d后出现中毒症状。临床表现为:眼睑下垂、吞咽困难、视物模糊、言语不清、肢体无力、呼吸困难及失眠伴焦虑不安等症状;其中1例出现Ⅱ型呼吸衰竭。所有患者给予抗感染、营养支持、抗焦虑及对症治疗,严重中毒患者行呼吸机辅助通气及血液灌流,均治愈出院。
Botulinum toxin（BTX） is a neurotoxin produced by Clostridium botulinum. BTX poisoning could cause multiple organ dysfunctions. All 6 patients were women aged 25-55 years. They developed poisoning symptoms 2-9 days after starting injection of BTX. Clinical manifestations included blepharoptosis,dysphagia,blurred vision,barylalia,weakness in the extremities,dyspnea,insomnia accompanied by agitation,and so on. One of them experienced respiratory failure Ⅱ. All the patients received anti-infection,nutritional support,anxiolytic and symptomatic therapy. Meanwhile the patients with severe poisoning received ventilator support and hemoperfusion. All patients recovered and were discharged.
出处
《药物不良反应杂志》
2010年第2期114-116,共3页
Adverse Drug Reactions Journal
关键词
肉毒素
美容
中毒
临床表现
救治
botulinum toxin
cosmetic procedures
poisoning
clinical manifestation
management
