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碱性成纤维细胞生长因子治疗视神经萎缩对视力和VEP的作用 被引量:1

Effect of basic fibroblast growth factor in treatment of optic atrophy on vision and visual evoked potential.
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摘要 目的:评估碱性成纤维细胞生长因子治疗视神经萎缩的疗效。方法:应用碱性成纤维细胞生长因子治疗视神经萎缩30例(39只眼),并与常规治疗(三磷酸腺苷、辅酶A)的病例进行对照观察,以视觉诱发电位作为治疗前后主要观察指标。结果:治疗组与对照组比较差异有显著性(P<0.01)。结论:碱性成纤维细胞生长因子是治疗视神经萎缩的更为有效的方法。 Objectives: To evaluate the therapeutic effect of basic fibroblast growth factor(bFGF) on optic atrophy.Methods:Thirty patients (39 eyes) with optic atrophy were treated by bFGF and the result was compared with that of patients treated by ATP and CoA.Results: A significant difference was noted between the treated and the control group( P <0.01) Conclusions: bFGF mught be an more effective drug for treating optic atrophy.
出处 《临床脑电学杂志》 1999年第1期11-12,共2页
关键词 BFGF 视神经萎缩 诱发电位 视觉 Basic fibroblast growth factor Optic atrophy Visual evoked potential Vision
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  • 1丁焕文,何锡煌.碱性成纤维细胞生长因子的生物学功能[J].中华创伤杂志,1995,11(3):189-191. 被引量:32
  • 2Abe K, Saito H. Effects of fibroblast growth factor on centry nervous system functions[J]. Phannacol Res, 2001,43(4):307 312.
  • 3Bennett N T, Schultz G S, Growth factors and wound healing: Biochemical properties of growth factors and their receptors[J]. Am J Surg, 1993,165:728.
  • 4Gospodarowicz D. Purification of a fibroblast growth factor from bovine pituitary[J]. J Biol Chem, 1975,250(7):2 515 -2 520.
  • 5Gambarini A G, Armlin H A. Purification and characterization of an acidic fibroblast from bovine pituitary[J]. J Biol Chem, 1982,257:9692- 9697.
  • 6Thomas K A. Purification and characrization of acidic fibroblast growth factor from bovine brain[J]. Proc Nail Acad Sci USA, 1984,81:357-361.
  • 7Bohlen P. Isolation and partial molecular characterization of pituitary, fibroblast growth factor[J]. Proc Nail Acad Sci USA, 1984,81:357-361.
  • 8Gospodarowicz D, Cheng J, Lui GM, et al.lsolation of brain fibroblast growth factor by heparine-sepharose affinity chromatograophy: identiy with pituitary fibroblast growth factor[J], Proc Nail Acad Sci USA, 1984,81(22) :6963 - 6967.
  • 9Cooke J P, Bhatnagar R, Szuba A, et al. Fibroblast growth factor as therapy for critical limb ischemia:a case report[J]. Vasc Med, 1999,4(2):89 - 91.
  • 10Walsh N, Valter K, Stone J. Cellular and subcellular parttems of expression of BFGF and CNTFin the normal and light stressed adult rat retina[J]. Exp Eye Res, 2001,72(5):495 - 501.

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