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上海市1950~1997年百日咳流行病学和免疫学效果分析 被引量:6

Epidemiological Analysis and Immunological Surveillance of Pertussis in Shanghai in 1950~1997
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摘要 上海市的百日咳发病率曾经高达1150.16/10万,使用百白破混合制剂(DPT)免疫及全程免疫接种率提高至90%后,使发病得到了有效控制.DPT的免疫学效果观察显示.免疫后较免疫前抗体增长40倍以上,阳转率和达保护抗体水平率分别高至90%和85%,吸附DPT的保护率约为96%.由此可见,有效的疫苗和高质量的免疫接种是控制百日咳流行的关键措施。 Morbidity of pertussis had been increasing significantly. When the immunization coverage rate of DPT was raised to more than 90% from 1980s to 1990s, the pertussis was effectively controlled. The immunological surveillance of DPT showed a perfectly effective antibody response of post-vaccination which increased 40 times higher than that of pre-vaccination, the positive seroconversion rate was more than 90% and the rate of GMT ≥1:320 was more than 85%. The protective rate of absorbed DPT vaccine was 96.64%. This indicates that a vaccine together with a high quality vaccenation are the most important measures for controlling pertussis.
出处 《中国计划免疫》 1999年第1期20-23,共4页 Chinese Journal of Vaccines and Immunization
关键词 百日咳 百白破混合制剂 全程免疫接种 流行病学 Pertussis DPT vaccine Complete immuinzation coverage rate Immune effect
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