超声内镜引导下腹腔神经节阻滞术治疗顽固性腹痛26例临床分析

The clinical experience of refractory abdominal pain treated by celiac plexus neurolysis under endoscopy ultrasonography guided in 26 cases

目的探讨超声内镜(EUS)引导下的腹腔神经节阻滞术(CPN)治疗顽固性腹痛的临床疗效。方法在线阵超声内镜引导下将药物注射于腹腔神经节区域,观察病人腹痛缓解情况。结果CPN的总有效率为96%,其中,12周疼痛缓解率为63.2%,24周疼痛缓解率为58%。结论EUS引导下CPN治疗是晚期胰腺癌、腹腔转移癌、慢性胰腺炎等引起的顽固性腹痛较安全、有效的镇痛方法。

Objective To study the clinical effect of refractory abdominal pain treated by celiac plexus neurolysis under endoscopy ultrasonography（EUS） guided.Methods EUS-guided celiac plexus neurolysis was performed under the guidance of linear array endosonography,the therapy effect was observed.Results Totally 96% was effective,63.2% was odynolysis within 12 weeks,58% was odynolysis within 24 weeks.Conclusion The refractory abdominal pain,including late stage pancreatic cancer,metastatic carcinoma of abdominal cavity,chronic pancreatitis,can be odynolysis effectively and safety treated by celiac plexus neurolysis under endoscopy ultrasonography guide.