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氟化钠对雄性大鼠血清肌酸激酶活力的影响

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摘要 目的:探讨不同剂量氟化钠对雄性大鼠血清肌酸激酶(CK)及其同工酶MB(CK-MB)的影响。方法:给4组共32只Wistar大鼠饲喂正常饲料,分别饮用含0.0、125.0、250.0、500.0 mg/L氟化钠(NaF)去离子水溶液2个月,复制氟中毒大鼠模型。饲喂2个月时取血,测定血清中CK及其CK-MB活力。结果:与对照组相比,染氟组大鼠血清CK及其CK-MB活力明显增加。结论:氟能引起雄性大鼠血清CK及CK-MB活力升高,可能引起心肌损伤。
出处 《包头医学院学报》 CAS 2010年第2期7-7,27,共2页 Journal of Baotou Medical College
基金 包头医药卫生基金项目(2008-15)
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参考文献2

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