日常外用药物及化妆品在高压氧舱内自燃可能性的研究

An investigation of the possible autoignition of external medicines and cosmetics in the hyperbaric oxygen chamber

目的系统地检测临床高压氧（ＨＢＯ）治疗中经常遇到的外用药物、用品及化妆品入舱的自燃可能性，以正确掌握防止随意性。方法用微型实验纯氧舱对９３种外用药物、用品及化妆品逐一进行模拟ＨＢＯ治疗实验检测。结果各被检物质在室温２２～２８℃、室内相对湿度６０％～８０％、舱中氧浓度９５％以上、实验压力０．３ＭＰａ（３ＡＴＡ）下，在９０分钟检测时间内未发生闪燃、自燃、着火及爆炸。结论ＨＢＯ治疗中始终应注意安全问题，但要按科学规律从事，避免过松和过严。

Objective Examining systematically the possible autoignition of external medicines and cosmetics generally used by the patients in the hyperbric oxygen(HBO) so as to handle correctly and avoid casualness.Methods Animal HBO mini chamber was self designed and installed. 93 KM mice were used, and one by one each with one of the 93 kinds of commonly used external medicines in surgery, dermatology, traumatology, ophthalmology and otolaryngology as well as cosmetics was examined separately in the HBO chamber.Results During the 90 minutes′ experiment in the HBO chamber none of the 93 tested substances appeared flash, autoignition, fire or explosion inside the HBO chamber(O 2%>95% and abs pressure 0.3MPa) with a room temperature of 22￣28 ℃ and relative humidity of 60%￣ 80%.Conclusions Special attention should be paid to the problem of safty during HBO treatment, and easy inflammable substances should not be brought into the HBO chamber. But scientific rule must be observed and casualness be avoided in making either too loose or over strict norms. The 93 kinds of tested substances in this experiment had not shown to produce autoignition in the routine HBO treatment chamber condition.