人工真皮修复软组织缺损20例

Repair of soft tissue defects with artificial dermis in 20 cases

为了研究及评价人工真皮在皮肤、组织缺损中的应用,北京积水潭医院烧伤科对2008-01/2009-04期间收治的皮肤、组织缺损患者20例应用人工真皮进行修复治疗。对有皮肤缺损、深部组织(肌腱、关节及骨外露)患者行清创、人工真皮移植,待其成活后,进行自体薄断层皮片进行移植,观察人工真皮及自体断层皮片的成活情况。移植后20例患者深部组织被有效覆盖,所有人工真皮成活,自体皮片移植成活,未见有明显瘢痕组织生成。提示应用人工真皮修复组织缺损、深部组织暴露,可以减少手术风险,减轻手术损伤,减轻瘢痕生成。

In order to study and appraise the application of artificial dermis in repairing skin defect or organization damage,20 patients underwent artificial dermis transplantation at the Department of Burn and Plastic Surgery,Beijing Jishuitan Hospital from January 2008 to April 2009 were collected.Patients with skin damage or depth portion organization （tendon,joint and bone appears externally） was perform debridement and artificial dermis transplantation,followed by split thickness autoskin transplantation.The survival of artificial dermis and split thickness autoskin was observed.After transplantation,the depth portion organization of patients were covered efficiently,all grafts survived without obvious scar proliferation.The results demonstrated that the prompt application of artificial dermis can reduce the surgery risk,relieve the surgery to damage,and reduce the scar production in repairing organization damage or depth portion organization expose.