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常用静脉麻醉药对腹腔镜胆囊切除术后呕吐的影响

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摘要 目的观察异丙酚、依托咪酯、硫喷妥钠诱导麻醉对腹腔镜胆囊切除术后呕吐的影响。方法同期腹腔镜胆囊切除术325例,随机分为3组:A组1f4例,诱导麻醉用异丙酚2mg/kg;B组107例,依托咪酯0.4mg/kg诱导;C组104例,25g/L硫喷妥钠5mg/kg诱导。其他诱导药物相同。维持麻醉用10g/L普鲁卡因,08g/L琥珀胆碱复合液。术后48h内双盲法观察呕吐情况。结果3组患者术后呕吐总发生率分别为47.4%、56.1%、452%(P〉0.05)。不同时间段呕吐发生情况,异丙酚组和硫喷妥钠组以术后6h以内发生最低(P〈0.01),且显著少于依托咪酯组(P〈0.01);6—12h异丙酚组最高,硫喷妥钠组次之(组内不同时间段均为P〈001),但该时间段三组间无差异。依托咪酯组术后24h内相对均衡。结论异丙酚和硫喷妥钠在腹腔镜胆囊切除术后早期抗呕吐作用明显。
作者 王淑卿
出处 《中国保健营养(下半月)》 2010年第5期162-163,共2页 China Health Care & Nutrition
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