儿童轮状病毒感染状况调查

Investigation of the infection of Rotavirus in children in Hangzhou area

目的对杭州地区儿童病毒性肠炎主要病原体轮状病毒（RV），进行分析，并了解轮状病毒流行病学特点。方法采用酶联免疫吸附试验（ELISA）法，对156例急性病毒性肠炎患儿粪便标本进行人类轮状病毒检测。结果在156例标本中共检出轮状病毒感染86例（55．1％），均为A组，人轮状病毒的感染对象主要为6～24月龄的婴幼儿，男女无明显的性别差异。结论轮状病毒是杭州地区婴幼儿病毒性腹泻的主要病原。且好发于2岁以内婴幼儿，无明显的性别差异，且临床表现较非轮状病毒感染组重。

Objective To research the infection of Rotavirus in children in Hangzhou area and to get the message of the feature of epidemiology. Methods Stool specimens of 156 children with suspected acute viral enteritis in Hangzhou between September 2006 and January 2008 were collected. Rotavirus were detected for all specimens by enzyme linked immunosorbent assay（ELISA）. Results Rotavirus was detected in 86 of 156 （55.1% ） specimens;all the 86 strains belonged to group A. The highest frequency of group A RV detected was 57% （70/123）in patients aged 6 -24 months. Conclusion The major pathogen of acute viral enteritis in children in Hangzhou area between September 2006 and January 2008 was RV. Children under the age of 2 years seemed to be more susceptible to RV infection than those of other age groups. The symptoms of RV enteritis were more severe than those of other viral enteritis.