血清(1-3)-β-D-葡聚糖检测对深部真菌感染患者的诊断价值

Diagnostic Value of Serum (1-3)-β-D-Glucan Detection in Diagnosis of Deep Mycosis

探讨血清(1-3)-β-D-葡聚糖检测对深部真菌感染患者的诊断价值及临床意义,应用MB—80微生物动态快速检测系统,及GKT—5MSet动态真菌检测试剂盒定量检测血清中(1-3)-β-D-葡聚糖的含量,从而统计出待检标本深部真菌感染的阳性率。结果60例可疑深部真菌感染患者,经传统培养方法诊断28例阳性,32例阴性,阳性率为46.7%;经血清(1-3)-β-D-葡聚糖检测33例阳性,12例为可疑感染,阳性率为55.0%,20例健康对照组均为阴性。说明血清(1-3)-β-D-葡聚糖检测较传统的真菌分离、培养与鉴定方法简便,快速,阳性率高,可用于深部真菌感染的早期诊断。

To explore diagnostic value of serum （1-3）-β-D-glucan detection in diagnosis of deep mycosis.content of serum （1-3）-β-D-glucan was detected by Microbiology Kinetic Rapid Detection System MB—80 and Kinetic Mycetes Detection Kit GKT—5M Set,thus to add up the masculine rate of mycotic infection of the examined sample.It is resulted that tested 60 samples of paients who are suspected to infect deep mycosis,there are 28 positive samples and 32 are negative by using traditional methods,the positive rate is 46.7%,when the detection of （1-3）-β-D-Glucan is used to diagnose the deep Mycosis infection,there are 33 positive samples and 27 negative samples,the positive rate reaches 55.0%.All of the samples in healthy control group are negative.It is conclused that：detection of serum （1-3）-β-D-glucan is much more convenient and faster than the traditional way.with its high positive rate,it can be used in the early diagnosis of deep mycotic infection.