短暂性脑缺血发作患者糖代谢异常的调查

Investigations of Glucose Metabolism Disorders in Patients with Transient Ischemic Attack

目的调查我院短暂性脑缺血发作(transient ischemic attack,TIA)住院患者的糖代谢异常情况。方法收集2007年7月～2009年5月在我院神经内科住院的经临床诊断为TIA的患者129例,记录患者临床资料及血糖等生化指标,对患者进行颅脑计算机断层扫描(computed tomography,CT)或磁共振成像(magnetic resonance imaging,MPI)、血糖等生化指标检查。结果本组129例TIA患者中,糖代谢异常72例(55.8%),其中糖尿病35例(27.1%),糖调节受损57例(28.7%);正常糖耐量57例(44.2%)。前循环TIA患者58例,糖代谢异常31例(55.4%);后循环TIA患者71例,糖代谢异常41例(57.7%),前后循环TIA患者糖代谢异常的频率无明显差异。结论 TIA患者合并糖代谢异常的比例较高,前、后循环TIA患者的糖代谢异常的发生率无明显差别,通过口服葡萄糖耐量试验(oral glucose tolerance test,OGTT)可以更准确地发现糖代谢异常。

Objective To investigate the glucose metabolism ofinpatients with transient ischemic attack （TIA）. Methods One hundred and twenty-nine inpatients with TIA from July 2007 to March 2009 were collected. We recorded the clinical features and biochemical indices of all patients. Head computed tomography （CT） or magnetic resonance imaging （MRI） was performed. Results In all patients, 72 cases （55.8%） had abnormal blood glucose, including 35 cases （27.1%） of diabetes and 37 cases （28.7%） impaired glucose tolerance; 57 cases （44.2%） were normal glucose tolerance. Fifty eight cases were anterior circulation patients, 31 cases were abnormal blood glucose （53.4%）; 71 cases were posterior circulation patients, 41 cases were abnormal blood glucose （57.7%）.The abnormal blood glucose frequency between anterior circulation and posterior circulation do not have statistical significance. Conclusion Most of TIA patients have impaired glucose regulation. In the frequency, anterior and posterior circulation patients with abnormal glucose metabolism do not have statistical significance. Oral glucose tolerance test （OGTT） can more accurately detect abnormal glucose metabolism patients.