生长抑素治疗消化性溃疡出血效果分析

Efficiency Analysis of Somatostatin for the Treatment of Peptic Ulcer Complicated by Upper Gastrointestinal Bleeding

目的:比较国产生长抑素与进口生长抑素治疗消化性溃疡出血的经济效果。方法:将120例消化性溃疡伴出血的患者随机分成国产生长抑素及进口生长抑素组,分别给予国产生长抑素、进口生长抑素治疗3天,观察疗效,并进行药物经济学评价。结果:国产生长抑素、进口生长抑素治疗上消化道出血成本分别为558元和4116元,有统计学差异(P<0.05);有效率分别为92.5%和96.8%,无统计学差异(P>0.05),成本—效果比分别为603.24和4252.07,有统计学差异(P<0.05)。结论:从药物经济学角度分析,国产生长抑素治疗消化性溃疡出血较进口生长抑素更为经济。

Objective： To evaluate the cost-efficiency of domestic-made somatostatin and imported somatostatin for the peptic ulcer complicated by upper gastrointestinal bleeding.Methods： Economic principle of pharmacology applied,the cost and efficiency of two kinds of treatments with domestic-made somatostatin and imported somatostatin were analyzed.Results： The cost of domestic-made somatostatin and imported somatostatin were 558 yuan and 4116 yuan respectively,with significant difference（P〈0.05）,the effective rates were 92.5% and 96.8% respectively,with no significant difference（P〉0.05）,and the cost-efficiency rate were 603.24 and 4252.07 respectively,with significant difference（P〈0.05）.Conclusion： Domestic-made somatostatin is an economical and effective option for the treatment of peptic ulcer complicated by upper gastrointestinal bleeding.