瞬态图形视觉诱发电位在2至5岁正常儿童视力评价中的应用研究

The transient PVEP acuity assessment for 2 to 5 years old normal children

目的探讨瞬态图形视觉诱发电位（PVEP）在2～5岁儿童视力评价中的应用。方法2007年9月至2008年1月，对179名（355只眼）2至5岁城市的正常儿童，进行图形视力和瞬态图形视觉诱发电位视力（PVEP-A）检测，并作对比研究。图形视力由儿童图形视力表进行单眼裸眼视力测试后得到，PVEP—A则是采用水平条栅翻转刺激诱导视觉诱发电位的方法检测。采用x^2检验及秩和检验方法对计数资料进行分析，将PVEP—A结果转换为国际标准视力，并与图形视力结果采用Logistic回归进行相关分析。结果179名儿童检测结果显示，图形视力随年龄增长而逐渐递增，且全部受试儿童图形视力均≥0．4。PVEP—A检测值也与年龄分布呈正相关，受试儿童PVEP—A均达到3．4c／d或以上。测试组间的PVEP—A差异均有统计学意义。瞬态PVEP-A与图形视力有较好相关性（r=0．673），且两眼PVEP-A差与两眼图形视力差的相关性系数r为0．664。显示受检儿童的PVEP-A发育早于图形视力。结论应用PVEP进行客观视力评估是一种目前较为方便、稳定、可靠的方法。

Objective To evaluate the practicality of transient PVEP （pattern visual evoked potential ,PVEP） acuity assessment for 2 to 5 years old normal children from September 2007 to January 2008. Methods Pattern acuity and transient PVEP-A of 179 （355 eyes） normal children between 2 to 5 years were detected and analyzed. Pattern acuity data were got from test for single uncorrected eye with pattern acuity table. PVEP-A was measured by the horizontal gratings evoked potention, vohich were cognizable response . x2and rank tests methods were used to analysis. The value of PVEP-A was converted to international standard acuity, and then comparison to pattern acuity with Logistic regression method. Results With the growth of age, pattern acuity was gradually increased and the value was greater than 0. 4. The positive correlation also existed among PVEP-A and age, PVEP-A from test children was all greater than 3.4 c/d. The analysis result of rank regression was P 〈 0. 01, that meaned PVEP-A difference among four groups had statistics significance. The correlation coefficient of PVEP-A with pattern acuity was good （ r = 0. 673 ）. The difference of PVEP-A and pattern acuity between two eyes was correlated （ r = 0. 664 ）. The result also pointed out PVEP-A growth was earlier than pattern acuity among 179 children. Conclusion Stabilization and reliability PVEP is a good objective visual assessment for younger and handicapped children.